Item contains two medical texts written by the ancient Greek physician Galen bounded into one volume. The first work, Galenus de ossibus (On bones for beginners), was translated by the Italian physician and humanist Ferdinando Balami was published in 1549. The second book, De usu partium corporis humani (On the use of the parts of the human body) was translated by the Italian scientist Niccolo da Reggio was published in 1550.

Item has a German pigskin binding. The front cover has an impression of a personification of Justice, and an impression of on the legendary Roman woman Lucrece on the back cover.